Physiological and pathophysiological roles for phospholipase D.
This post was originally published on this site Individual members of the mammalian phospholipase D (PLD) superfamily undertake roles that extend from generating the second […]
What next-generation sequencing (NGS) technology has enabled us to learn about primary autosomal recessive microcephaly (MCPH).
This post was originally published on this site The impact that next-generation sequencing technology (NGS) is having on many aspects of molecular and cell biology, […]
Congenital imprinting disorders: Application of multilocus and high throughput methods to decipher new pathomechanisms and improve their management.
This post was originally published on this site Imprinting disorders (IDs) are a group of congenital diseases affecting growth, development and metabolism. They are caused […]
Promise and Pragmatism in Clinical Microbiome Research.
This post was originally published on this site The evolution of human microbiome research has lead to a systems biology approach that encompasses multidisciplinary investigations. […]
Genomic Profiling of Biliary Tract Cancers and Implications for Clinical Practice.
This post was originally published on this site OPINION STATEMENT: Biliary tract cancers are relatively uncommon, have an aggressive disease course and a dismal clinical […]
The genetics and pathology of mitochondrial disease.
This post was originally published on this site Mitochondria are double membrane-bound organelles that are present in all nucleated eukaryotic cells and responsible for the […]
The genetics of uveal melanoma: current insights.
This post was originally published on this site Uveal melanoma (UM) is the most common malignant eye tumor in adults affecting ~7,000 individuals per year […]
Current concepts on the molecular pathology of non-small cell lung carcinoma.
This post was originally published on this site Recent advances in the understanding of the complex biology of non-small cell lung carcinoma (NSCLC), particularly activation […]
[Emerging Technologies Support the Molecular Basis of the WHO Classification of Hematopoietic Neoplasms].
This post was originally published on this site In the laboratory diagnosis of hematological neoplasms based on the WHO classification, molecular-genetic testing is indispensable. Emerging […]
Mutations in the noncoding genome.
This post was originally published on this site PURPOSE OF REVIEW: Clinical diagnostic sequencing currently focuses on identifying causal mutations in the exome, wherein most […]