Next-Generation Sequencing and the Return of Results.

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Next-Generation Sequencing and the Return of Results.

Cold Spring Harb Perspect Med. 2016 Oct 03;6(10):

Authors: Knoppers BM, Nguyen MT, Sénécal K, Tassé AM, Zawati MH

Abstract
The impact of next-generation sequencing (NGS) on the issue of return of results is defying clear policy guidance and creating international confusion. Limiting ourselves to the return of results revealed by NGS (including incidental findings) in adults, children, family members of deceased individuals, and population studies, we describe and contrast emerging policy positions in Europe, Canada, and the United States. Until there are clear, scientific, and professional standards and practical policy, both researchers and clinicians cannot be faulted for being either hesitant or pressured to return NGS results.

PMID: 27599532 [PubMed – indexed for MEDLINE]

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