Real world data (RWD) promise to provide a pivotal element to the understanding of personalized medicine. But without true representation (or the reality) of the patient-disease biosystem and its molecular contributors, RWD may hamper rather than help this advancement. In this review article we discuss the following: RWD verses clinical reality and the disconnects that exist currently (emphasizing molecular medicine), and lastly, methods of closing the gaps between RWD and reality. This article is protected by copyright. All rights reserved.
© 2015 American Society for Clinical Pharmacology and Therapeutics.