2.0: Genome resources and website updates.

Chinese hamster ovary (CHO) cells are a major host cell line for the production of therapeutic proteins, and CHO cell and Chinese hamster (CH) genomes have recently been sequenced using next-generation sequencing methods. was launched in 2011 (version 1.0) to serve as a database repository and to provide bioinformatics tools for the CHO community. (version 1.0) maintained GenBank CHO-K1 genome data, identified CHO-omics literature, and provided a CHO-specific BLAST service. Recent major updates to (version 2.0) include new sequence and annotation databases for both CHO and CH genomes, a more user-friendly website, and new research tools, including a proteome browser and a genome viewer. CHO cell-line specific sequences and annotations facilitate cell line development opportunities, several of which are discussed. Moving forward, will host the increasing amount of CHO-omics data and continue to make useful bioinformatics tools available to the CHO community.

Copyright © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Be the first to comment

Leave a Reply

Your email address will not be published.