Valuable lessons-learned in transcriptomics experimentation.

Figure 1.

Smoothing effects of improper averaging over individuals. Time profiles of Log2 fold change compared to t = 0 of the Mdm2 gene in skin derived from an in vitro mouse study. The mice were treated with UV-B at t = 0. (A) Averaged profiles over biological replicates for both treated and untreated samples. (B) Profiles of individual mice that were not treated. Different colors indicate individual mice. (C) Profiles of individual mice that were irradiated with a high dose of UV-B. Different colors indicate individual mice.

Transcription. 2015 May-Jun;6(3):51-55.

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