Electronic Journal of Medical Genetics

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Month: August 2016

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Translating RNA sequencing into clinical diagnostics: opportunities and challenges.

August 31, 2016 admin 0

With the emergence of RNA sequencing (RNA-seq) technologies, RNA-based biomolecules hold expanded promise for their diagnostic, prognostic and therapeutic applicability in various diseases, including cancers and infectious diseases. Detection of gene fusions and differential expression […]

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Precision medicine in NSCLC and pathology: how does ALK fit in the pathway?

August 31, 2016 admin 0

The evolution of personalised medicine in lung cancer has dramatically impacted diagnostic pathology. Current challenges centre on the growing demands placed on small tissue samples by molecular diagnostic techniques. In this review, expert recommendations are […]

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ALK evaluation in the world of multiplex testing: Network Genomic Medicine (NGM): the Cologne model for implementing personalised oncology.

August 31, 2016 admin 0

Comprehensive molecular genotyping of lung cancers has become a key requirement for guiding therapeutic decisions. As a paradigm model of implementing next-generation comprehensive diagnostics, Network Genomic Medicine (NGM) has established central diagnostic and clinical trial […]

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Exploiting the potential of next-generation sequencing in genomic medicine.

August 31, 2016 admin 0

INTRODUCTION: The review highlights the impact of next-generation sequencing (NGS) on genomic medicine and the consequences of the progression from a single-gene panel technology to a whole exome sequencing approach. AREAS COVERED: We brought together […]

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Tasmanian devils evolve to resist deadly cancer

August 31, 2016 admin 0

Study could direct future research on cancer remission, recurrence. Tasmanian devils are evolving in response to a highly lethal and contagious form of cancer, a Washington State University researcher has found. Andrew Storfer, WSU professor […]

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Genome-wide association studies (GWAS) and their importance in asthma.

August 30, 2016 admin 0

Asthma is a complex disease determined by the interaction of different genes and environmental factors. The first genetic investigations in asthma were candidate gene association studies and linkage studies. In recent years research has focused […]

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Ethnic diversity in the genetics of venous thromboembolism.

August 30, 2016 admin 0

Genetic susceptibility is considered as a crucial factor for the development of venous thromboembolism (VTE). Epidemiologic and genetic studies have revealed clear disparities in the incidence of VTE and the distribution of genetic factors for […]

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Repertory of eukaryotes (eukaryome) in the human gastrointestinal tract: taxonomy and detection methods.

August 30, 2016 admin 0

Eukaryotes are an important component of the human gut, and their relationship with the human host varies from parasitic to commensal. Understanding the diversity of human intestinal eukaryotes has important significance for human health. In […]

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[Whole-Exome Sequencing for monogenic disorders affecting the orthopaedic system].

August 30, 2016 admin 0

Next-generation sequencing technologies enable comprehensive genetic analyses in monogenic and oligonenic diseases. Especially whole-exome sequencing(WES)targeting exonic regions of protein coding genes is mainly used for Mendelian diseases. Here we describe a case of Hand-foot-genital syndrome […]

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[Application of big data analyses for musculoskeletal cell differentiation].

August 30, 2016 admin 0

Next generation sequencer has strongly progress big data analyses in life science. Among various kinds of sequencing data sets, epigenetic platform has just been important key to clarify the questions on broad and detail phenomenon […]

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Recent Posts

  • Tymora Develops Method for Proteomic Analysis of Extracellular Vesicles
  • Inhaled blood pressure drug could prevent panic attacks
  • TGen Team Hopes $2M Study Will Help Lay Path for Liquid Biopsy Monitoring in Metastatic Melanoma
  • GWAS Links Six New Loci to Multiple Myeloma Risk, Uncovers Potential Mechanisms
  • Bristol-Myers Squibb to Use Natera's Cell-Free DNA Assay in Immunotherapy Study

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