Next Generation Sequencing and Multi-Gene Panel Testing: Implications for the Oncology Nurse.
Semin Oncol Nurs. 2017 Apr 05;:
Authors: Kelly PA
OBJECTIVES: To review past, current, and future events in genetics and discuss how genetic testing information personalizes cancer screening, detection, and treatment. A case study is presented to illustrate key points.
DATA SOURCES: National guidelines, evidence-based summaries, peer-reviewed studies, editorials, and web sites.
CONCLUSION: Multi-gene testing using next-generation sequencing has changed the landscape for hereditary cancer syndromes.
IMPLICATIONS FOR NURSING PRACTICE: Nurses have key roles in personalizing health care including recognizing the complexities of genetic testing, assessing family history, understanding gene/environment factors, referring for genetics consultations, and promoting registry studies. In order to be effective, nurses must stay current with the rapidly-changing technology and guidelines for genetic evaluations and testing.
PMID: 28390840 [PubMed – as supplied by publisher]