Environments Tune and Select Cellular Diversity.
Trends Immunol. 2017 Sep;38(9):617-618
Authors: Kidd BA
Technical advances in single-cell sequencing data and their application to greater samples is revealing substantial cell-to-cell variation in expression levels and propagation of this variation between molecules across cells. New quantitative approaches that apply mechanistic and statistical models in a systems-wide approach are illuminating the drivers of phenotypic diversity.
PMID: 28774723 [PubMed – indexed for MEDLINE]