Cell-Free DNA Purification Kit Comparison Shows Spin Column Tech Superior

NEW YORK (GenomeWeb) – A group of researchers led by the Macquarie University in Sydney, Australia have compared a variety of commercial kits on their ability to extract circulating cell-free DNA (cfDNA)from patient blood samples.

The team found that, in general, spin column-based extraction kits — such as Qiagen’s QIAamp circulating nucleic acid kit and Norgen’s Biotek’s Plasma/serum cell-free circulating DNA Purification midi kit (NorS) — performed better than more recently introduced magnetic bead-based kits.

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