A new gene therapy approach designed to replace the enzyme that is deficient in patients with Tay-Sachs and Sandhoff diseases, inherited neurodegenerative disorders, successfully delivered the therapeutic gene to the brains of treated mice, restored […]
A new study, led by scientists at The Scripps Research Institute (TSRI), reveals a surprising twist in immune biology. The research in animal models suggests that members of a cluster of microRNAs (miRNAs) – small […]
In one of the largest international genetic studies of congenital heart disease (CHD), researchers have discovered gene mutations linked to three new rare congenital heart disorders. Published in Nature Genetics, the researchers also found the […]
Plasmids are pieces of independent DNA that often carry multiple antibiotic resistance genes. Plasmids can jump from one bacterium to another, spreading that resistance. A team of French investigators now shows that bacteria that acquire […]
The discovery of 15 regions of the genome associated with major depressive disorder (MDD) in individuals of European descent is reported in a study published online this week in Nature Genetics. The study represents the […]
Results from a study published in the online publication Nature Genetics finds 15 genomic regions that are significantly associated with a diagnosis of depression. Identifying genes that increase the risk for depression may help researchers […]
Having a higher body mass index may not increase the risk of heart attack or death, though it does raise the risk of type 2 diabetes. These are the findings of a twin study published […]
Scientists have developed a new method of measuring the activity of disease-causing mutations in the LRRK2 gene, a major cause of inherited Parkinson’s disease. The team believes this breakthrough, which is published in the Biochemical […]
The formation of large numbers of polyps in the colon has a high probability of developing into colon cancer, if left untreated. The large-scale appearance of polyps is often due to a hereditary cause; in […]
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